Commercialisation: delivering tools, germplasm and cultivars to industry

The Molecular Plant Breeding CRC established a corporate structure to facilitate the commercial adoption of technologies and inventions developed by its participants.

It aimed to commercialise the outcomes of its research for the benefit of Australia in general and Australian farmers in particular. Obtaining utilisation of advanced technologies was considered to be more important than revenue generation per se but the project portfolio was managed with a view to generating a reasonable return to the financial and resource contributions of the Government and CRC participants.

Breeding new varieties takes a long time and the new cultivars that will benefit from the CRC's work will not reach the market until several years after the CRC has finished. Due to these long time frames, instead of trying to commercialise cultivars only after completing the development process MPBCRC sought to attract commercial funding into research programs at an early stage. This strategy enabled the CRC to attract many millions of dollars of additional funding which facilitated the development of more robust and ambitious projects than would otherwise have been possible.

Three examples of this are:

  • A $28 M collaborative R&D Program with BASF Plant Science to develop GM wheats that are drought tolerant and fungal resistant.
  • A $36 M incorporated joint venture, Gramina Pty. Ltd., with PGG Wrightson Ltd. (New Zealand) to develop GM forage grasses with improved nutrition and digestibility.
  • A $6 M project to develop genetic markers for desirable forage traits, supported by Dairy Australia, Meat and Livestock Australia and the Geoffrey Gardiner Dairy Foundation.
     

Intellectual Property

Molecular Plant Breeding generated the following patents during its lifetime.

  

Patent Title

Technology Area

Patent /Application No.

Fructosyl transferase homologues from ryegrass and fescue species Genes and promoters for the manipulation of fructan biosynthesis. Useful for increasing the nutritive value of pasture grasses New Zealand: 523032
Australia: 2001265676
Europe: 01942880.4
Denmark: DK1305420
France: FR1205420
Germany: DE1305420
Netherlands: NL1305420
Spain: ES1305420
UK: GB1305420
USA: 7557261
Modification of plant resistance to diseases and/or pests Genes for an O-methyltransferase homologue, the manipulation of expression of which provides increased resistance to disease and other pests New Zealand: 523538
Australia: 2001276169
USA: 7122718
Manipulation of plant life-cycles and/or growth phases Genetic sequences, the expression of which may be manipulated to alter the growth phase of plants, such as by increasing or decreasing vegetative growth, or delaying the onset of flowering. This provides the ability to enhance herbage quality and increase biomass yield New Zealand: 525585
Australia: 2002213672
Use of bi-functional alpha amylase-subtilisin inhibitor promoter to direct expression in pericarp of plants Use of a promoter sequence that directs expression to the pericarp of plants Australia: 2003271420
Pollen promoter Promoter sequence driving specific expression in the pollen of plants. Useful for effect outcomes such as the down-regulation of pollen allergen genes Australia: 200429788
USA: 7355096
New Zealand: 544217
Europe: 0473725.9

Method of amplifying nucleic acid

Temperature switch PCR

Australia: PCT/AU08/001396
Argentina: 08 01 04100
Canada: 2,697,532
Europe: 08800031.0
USA: 12/678,874

Method for wheat transformation using Agrobacterium

A method for inserting useful genes into the wheat genome

Australia: 2006900826

Plant Promoter I
Plant Promoter II
USA (provisional filing)
USA (provisional filing)
Plant technology A method for increasing the nutritional content and increasing the growth rate of plants International: PCT/AU2009/001211
Argentina: TBA
Pakistan: 850/2009
Thailand: 9091004173
Taiwan: 98130928
Uruguay: 32.117
Venezuela: 2009-001669
Plant promoter 1 A plant promoter driving genetic expression in the endosperm International: PCT/AU2010/000430
Plant promoter 2 A plant promoter driving expression in the basel endosperm transfer layer (BETL) PCT/AU2010/000553
Endophytes Novel endophytic fungi Two provisional filings
Multiplex ready technology Facilitates microsatellite genotyping International: PCT/AU06/000318
Improved mapping method for polyploid subjects Facilitates genotyping of wheat (aka ddSNP) International: PCT/AU2008/001397
Argentina: 08 01 04101
Modification of lignin biosynthesis via sense suppression A method of reducing lignin by application of sense suppression

International    
     : PCT/AU08/001034
     : WO09/009830
Argentina: P080103127
Uruguay: 31.242
Australia: 2008278274
New Zealand: TBA
Brazil: PI0913206-2
China: TBA
Europe: TBA
India: TBA
USA: TBA


 

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